The analysis involved using a multi-omic single nucleus study of 191,890 nuclei in late-stage Alzheimer’s Disease (AD). This is just a brief explanation of the finding based on the dataset.

The RNA data was analyzed using Principal component analysis (PCA). Most expressed genes were found using PCA.

The analysis was done using R studio.

RNA Expression using Principal component analysis (PCA).

The function of MR-RNR2 is responsible for protein binding. A dysfunctional MR-RNR2 gene could result in a negative apoptotic process.  

STC1 gene involved homeostasis in regulating calcium ion. Alzheimer’s patients often have either up-regulated or down-regulated calcium in their blood stream.

More analysis coming soon!.

Visualization of Age, Protein Tangle Stage in Alzheimer’s Disease & Control. Protein Tangle is Stage 1 & 2 and Stage 5 & 6
Visualization of Sex (Female/Male), Protein Tangle Stage in Alzheimer’s Disease & Control. Protein Tangle is Stage 1 & 2 and Stage 5 & 6
Visualization of Sex (Female/Male), Age in Alzheimer’s Disease & Control.